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Natural genetic variation on Chromosome V confers resistance to the widely-used insecticide Chlorfenapyrin C. elegans.

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Exposure to environmental toxicants poses significant harm to humans. However, assessing the risk for diverse human populations is challenging because genetic differences among individuals can cause disparities in toxicant susceptibilities. We will use genetically diverse C. elegans strains (obtained from CaeNDR) isolated from around the world as a model to study how natural variation can affect susceptibility to the widely-used insecticide chlorfenapyr.


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